Advances in systems science, including high throughput ‘omics’ technologies and bioinformatics, have contributed to a radically new understanding of inflammation. For example, it is now recognized that acute inflammation does not end passively but is actively controlled by a complex network of signaling molecules that become most prevalent during a second phase of inflammation named inflammation resolution. The most well characterized signaling molecules controlling inflammation resolution are derivatives of n-3 and n-6 polyunsaturated fatty acids (PUFAs) and are named specialized pro-resolving lipid mediators (SPMs). SPMs are found in low concentrations throughout the body as a superfamily of structurally related molecules named lipoxins, resolvins, maresins and their associated conjugates. In addition to promoting inflammation resolution, SPMs also regulate pain, accelerate and support tissue healing, improve lymphatic system functions, prevent infection, reduce oxidative stress, control central nervous system (CNS) signaling and regulate stem cell activity.
David W Lescheid works as a freelance Medical Writer and consultant providing scientific material and delivering lectures that help support patient care using Integrative medical principles. He also works part-time teaching Leadership workshops to scientists as well as part-time as the MedicoScientific Manager of the International Academy of Bioregulatory Systems Medicine in Baden-Baden, Germany. Prior to these current positions, Dr. Lescheid was a Professor at the Canadian College of Naturopathic Medicine where he taught Physiology, Microbiology and Infectious disease as well as Clinical Care. Additionally, he spent four years practicing full-time in a large multidisciplinary health clinic in Ottawa with specialized interests in the immune system and infectious disease, men’s health issues, obesity concerns, and sports medicine. He has been a member of several federal and international committees including the Expert Advisory Committee (EAC) to Health Canada, the Council for Naturopathic Medical Education (CNME), the Canadian Association of Naturopathic Doctors (CAND), and other government and media relations subcommittees. Dr. Lescheid graduated with honors from the Canadian College of Naturopathic Medicine (CCNM) in 2002. He earned his Ph.D. in Molecular Biology and Protein Chemistry from the University of Victoria. He completed his B.Sc. in Biology, earned a Diploma in Health and Fitness studies from Simon Fraser University, and has additional training in IV therapies, homotoxicology, homeopathy and different forms of bodywork. Dr. Lescheid is a frequent guest speaker at various international medical and scientific seminars, and has published extensively on complementary and integrative medicine.
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