Probiotics for Enhancement of Athletic Endurance and Performance by Dr. Venket Rao, PhD

Probiotics for Enhancement of Athletic Endurance and Performance by Dr. Venket Rao, PhD

Recently, great interest both from clinical research as well as from health practitioners has focused on enhancing the performance and endurance of amateur as well as professional athletes. Traditionally, athletes have used performance enhancing drugs such as anabolic steroids in improving their performance. Many of the drugs including anabolic steroids, peptide hormones, beta-2 agonists, hormone and metabolic modulators as well as diuretics and masking agents are now banned mainly for the reason that they pose increased health risks. As a result, renewed interest has surfaced in the possibility of nutritional supplements being used in improving athletic performance and endurance, with...

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Efficacy of High-Dose EPA Omega-3: Prevention and Management of Chronic Disorders Including Cardiovascular Disease by Dr. Bruce Holub, PhD

Efficacy of High-Dose EPA Omega-3: Prevention and Management of Chronic Disorders Including Cardiovascular Disease by Dr. Bruce Holub, PhD

Increased intakes of long-chain polyunsaturated omega-3 fatty acids in the form of EPA eicosapentaenoic acid (20:5 n-3) having 20 carbons in chain length and 5 double bonds (unsaturation sites between adjacent carbon atoms in the molecule) and DHA (22:6 n-3) with 22 carbons and 6 double bonds are well known to provide robust human health benefits. These include the prevention and complementary management of wide-ranging chronic disorders. Numerous human studies and clinical trials as published in the peer-reviewed medical/nutrition literature exhibiting such health benefits have provided EPA and/or DHA via nutritional supplements at daily levels which are safe but well above...

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Webinar on Viva la Vagus: The Neural Control of Inflammation By Dr. David W Lescheid

Webinar on Viva la Vagus: The Neural Control of Inflammation By Dr. David W Lescheid

It is well known that persistent inflammation is a key driver of many different chronic diseases. Our current scientific understanding of the inflammatory response now includes evidence that acute inflammation is actively controlled by a resolution phase, which uses different mediators as stop signals and checkpoints for pro-inflammatory signals. Moreover, neuroendocrine pathways, including those from the hypothalamic-pituitary-adrenal axis, sympathetic nervous system, and vagus nerve, also actively help to resolve acute inflammation and prevent it from becoming chronic and causing pathology. These recent scientific discoveries support the need to treat all regulatory control hubs of inflammation, including cellular, humoral and neural...

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The Association of Two Pandemics: COVID-19 and Vitamin D deficiency by Dr. Michael Traub

The Association of Two Pandemics: COVID-19 and Vitamin D deficiency by Dr. Michael Traub

March 11, 2020, the World Health Organization announced the novel coronavirus disease (COVID-19) outbreak to be a global pandemic. The incidence of new COVID-19 cases has continued to accelerate, while the incidence of new deaths has remained relatively stable.  As of October 18, over 40 million cases and 1.1 million deaths had been reported globally, with over 2.4 million new cases and 36,000 new deaths reported in the preceding week. (1) Vitamin D deficiency has also been described as pandemic, especially in Europe. Regardless of age, ethnicity, and latitude, recent data show that 40% of Europeans are vitamin D deficient...

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Enriched Marine Oil Supplements Increase Peripheral Blood Specialized Pro-Resolving Mediators Concentrations and Reprogram Host Immune Responses: A Randomized Double-Blind Placebo-Controlled Study by David W. Lescheid, N.D., Ph.D.

Enriched Marine Oil Supplements Increase Peripheral Blood Specialized Pro-Resolving Mediators Concentrations and Reprogram Host Immune Responses: A Randomized Double-Blind Placebo-Controlled Study by David W. Lescheid, N.D., Ph.D.

Recent scientific advances demonstrate that acute inflammation includes at least three different phases named initiation (or onset); resolution; and post-resolution (or adapted homeostasis). All three of these phases must occur in a controlled fashion over time for optimal healing to occur in an acutely inflamed tissue. Resolution of acute inflammation is an active process that uses a number of different mediators including specialized pro-resolving lipid mediators (SPMs) to act as checkpoints and stop signals to the mediators of the proinflammatory or initiation phase. Most SPMs are synthesized from omega-3 fatty acid metabolites such as docosahexanoic acid (DHA), eicosapentanoic acid (EPA),...

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L- Carnitine: An Under-utilized Superstar by Dr Philip Rouchotas, ND

L- Carnitine: An Under-utilized Superstar by Dr Philip Rouchotas, ND

L- carnitine is an ultra-versatile under-utilized superstar in the tool bag of the integrative healthcare provider. The goal of this review is to reacquaint readers with this safe, effective, and cost-effective intervention. A quick search of PubMed revealed 65 meta-analytic and systematic reviews of this agent. A selection of these will be presented below. L- carnitine serves as a transporter of free fatty acids greater than 14 carbons in length to be shuttled into the inner mitochondrial matrix where they enter the beta oxidation pathway. L-carnitine is present in greatest concentration in skeletal and cardiac muscle, yet is found in...

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Fish oils are NOT blood-thinners by Dr Neil McKinney, ND

Fish oils are NOT blood-thinners by Dr Neil McKinney, ND

Omega 3 oil is a marvelous natural anti-inflammatory and is also associated with positive changes in hypertriglyceridemia. These properties would be expected to give a great benefit in cardiovascular diseases (CVD). Somehow many doctors and scientists have attributed to fish oils the property of anti-coagulation. Thinning of the blood would be of concern if the patient is on blood-thinning drugs, has had hemorrhagic disorders, or is about to have surgery. Scientists from Holland looking at the health of Inuit and Eskimo in the 1970s found low rates of CVD, and attributed this largely to intake of fish and blubber (seal,...

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Green Tea and Reduction of Breast Cancer Risk and Recurrence by Dr Tori Hudson, ND

Green Tea and Reduction of Breast Cancer Risk and Recurrence by Dr Tori Hudson, ND

As clinicians, you likely already know of the many health benefits of green tea, and likely some of you are already familiar with some of the research on green tea and breast cancer risk reduction and recurrence. Based on a study some years back, I have been advising women with stage I and II breast cancer to drink 5 cups/day or take a select number of capsules per day (amount is based on the dose per capsule ). This current meta-analysis is a good update on the topic. The purpose of this systematic review and meta-analysis was to evaluate green tea...

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The role of mitochondria during viral infections by Dr. David W Lescheid, PhD

The role of mitochondria during viral infections by Dr. David W Lescheid, PhD

Historically, mitochondria were considered primarily as the ‘powerhouses of the cell’ because they contain the major biochemical pathways needed to produce ATP energy. However, mitochondria also have many other functions including biosynthesis of amino acids, nucleotides, cholesterol and glutathione as well as control of antioxidant defences, redox status, apoptosis and autophagy.1, 1 Mitochondria also are key controllers of the response to numerous stressors,2 including infection, tissue injury and metabolic dysfunction.3 This paper will summarize the recently discovered roles of mitochondria in regulating immune responses,4, 5 especially those necessary for fighting viral infections. Mitochondrial signals that regulate immune responses include reactive...

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