SNP NUTRIGENETICS TEST
The Nutrigenetics Test Kit evaluates 60 SNPs for genes that code for enzymes identified as being important in natural health product metabolism using DNBseq Human whole genome sequencing. The kit provides a saliva swab and a return address envelope for the patient’s sample to be returned directly to our partner’s processing laboratory. Samples are coded to ensure anonymity (see accompanying disclosure and consent form for more information on protection of personal information). Laboratory results as well as an interpretation of findings from a health management standpoint are provided to the practitioner who requested the test for consultation with their patient.
The SNP Nutrigenetics test is available for the promotional price of CAN $245.
Turnaround time: 8 weeks.
Please sign into your NFH online account to order, or contact head office at 1 866 510 3123 or by e-mail mychrome@nfh.ca
Please use the following form to place your order:
Healing begins from within, any therapeutic approach must hence speak to the very core make-up that truly defines who we are and celebrates it. Would you like to revolutionize your clinical practice by crafting each treatment to the true unique genetic personality of your patient? Do you think it would be possible to modulate your patients’ metabolic pathways to optimize their health?
The rapidly gaining popularity of personalized genetic testing has resulted in a plethora of direct-to-consumer (DTC) genetic testing companies that offer genetic tests and in some cases, generalized nutritional and food recommendations. However, now armed with the utmost of knowledge of genetic predisposition, questions arise over whether the average consumer can process and act on this information in a beneficial manner. Unlike, these DTC companies, “NFH SNP Nutrigenetics Test” helps healthcare professionals understand their patients’ genetic profile by providing evidence based nutrigenetic research information. In addition, “NFH SNP Nutrigenetics Test” empowers healthcare professionals to utilize such valuable information and translate results into meaningful therapeutic protocols. “NFH SNP Nutrigenetics Test” guides healthcare professionals to offer personalized high quality supplements that cater specifically to each patient’s genetic and nutritional status.
Differences are after all what make us who we are. Let us celebrate these differences, and usher in a new approach to reaping further benefits of natural product therapeutics.
NFH is a valuable clinical tool meticulously crafted by scientists who are pioneers in personalized nutrition and in collaboration with BGI Americas Corporation.
| Component | Gene, rs Number |
| Mood & Behavior COMT activity and dopamine life Brain-derived Neurotrophic factor |
COMT, rs4680 BDNF, rs6265 MAOA, rs909525 MAOA, rs6323 MAOB, rs1799836 MAOB, rs10521432 GAD1, rs3791850 |
| Cardiovascular Health NOS response & NO Bioavailability APOE |
NOS3s, rs1799983 |
| Methylation Bioavailability of cytosolic 5-MTHF & efficiency of homocysteine to methionine conversion |
SHMT1, rs1979277 MTR, rs1805087 MTRR, rs1801394 MAT1A, rs1985908 MAT2B, rs4869089 |
| Insulin Response and Diabetes Risk | TCF7L2, rs12255372 IL-6, rs1800795 TNF-alpha, rs1800629 |
| Detoxification Enzyme function and clearance of substrates and reactive oxygen species |
SOD2, rs4880 CYP1B1, rs1056836 |
| Inflammatory Bowel Disease and Mitochondrial Function | SLC22A5, rs17622208 |
| Urea Cycle | CPS1, rs1509821 CPS1, rs6435580 |
| Detoxification and Cancer | CYP1A1*4 C2453A, rs1799814 |
| Vision Health | BCM01, rs1164528 |
| Choline Deficiency and Nafld | PEMPT, rs7946 |
| Mental Health | PEMT, rs4244593 |
| Autism | CBS, rs234706 |
| Folate Levels in Women | SLC19A1, rs1051266 |
| Cancer Susceptibility | CYP1A2, rs762551 |
| Detoxification and Susceptibility to Develop Gall Stones | SULT, rs2547231 |
| Oxidative Stress and HDL-C Levels | SOD3, rs2855262 |
| Component | Gene, rs Number |
| Vitamin B12 | FUT2, rs601338 |
| Vitamin D | CYP2R1, rs10741657 GC, rs2282679 |
| Folate | MTHFR, rs1801133 |
| Iron Overload | SLC17A1, rs17342717 HFE, rs1800562 HFE, rs1799945 |
| Low Iron Status | TMPRSS6, rs4820268 TFR2, rs7385804 TF, rs3811647 |
| Calcium | GC, rs7041 GC, rs4588 |
| Omega-3 Fat | NOS3, rs1799983 |
| Energy Balance | UCP1, rs1800592 |
| Saturated and Unsaturated Fat | FTO, rs9939609 |
| Cholesterol Lowering | CYP7A1, rs3808607 APOE rs7412 APOE rs429358 |
| Omega-3 Fat Utilization | FADS1 (rs174537, rs174545 & rs174561) FADS2, rs174583 |
| Autoimmune Disease Risk | PTPN22, rs2476601 CTLA, rs231775 |
Each of us has our own personality in many different ways, but particularly in our genetic makeup. These distinctions in genetic architecture are increasingly being linked to the differences that exist across people in the way they respond to nutritional and natural health products. At one time, it was considered that such heterogeneity in responsiveness was due to the failure of patients to comply with their prescriptions; however, intervention studies where intakes were closely monitored show that some people fail to respond to a supplement even with confirmed longer-term exposures. As such, this variability has presented a difficulty for health professionals to treat their patients with supplements that deliver optimal efficacy on a one on one basis.
A series of predictive response tests for natural health products based on genetics would be useful in minimizing the impact of interindividual variability in the effectiveness of natural products, by developing alternative therapeutic approaches and modified dosages to invigorate the confidence with which healthcare professionals and patients can use these products.
NFH’s scintillating scientific and medical advisory boards feature leading international experts in scientific and clinical practice. NFH enjoys being one of its kind as it is developed and fueled by these key experts specializing and serving the entire spectrum of science, technology, translational research, and clinical practice. Current platforms are based only upon information based on a single SNP, which provides less specific guidance than the use of multiple SNPs or gene sets, that the NFH Testing platform sets to explore using our unique cadre of approaches.
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